Ohio Assessment for Educators (OAE) Integrated Science (024) Practice Exam

In which stage of meiosis do cells prepare for separation into gametes?

1. Metaphase II

2. Anaphase II

3. Prophase II

4. Telophase II

The correct answer is: Metaphase II

The correct answer is that cells prepare for separation into gametes during Metaphase II. In this stage of meiosis, the chromosomes, which consist of two sister chromatids, align at the metaphase plate in the center of the cell. This alignment is critical because it ensures that when the chromatids are pulled apart during the following stage, each resulting gamete will receive one copy of each chromosome. Metaphase II is crucial for genetic stability and the formation of viable gametes because it sets the stage for the proper distribution of genetic material. The precise arrangement of chromosomes at the metaphase plate allows for an equal separation during Anaphase II, ensuring that each gamete contains a complete set of genetic information. In the context of the other options: Anaphase II is where the sister chromatids actually separate and move toward opposite poles of the cell. Prophase II involves the preparation of the cell for division but does not directly lead to separation. Telophase II occurs after separation has begun, leading to the formation of four haploid daughter cells from the two original cells, but it is not the stage where preparation occurs. Hence, Metaphase II is the correct stage for the preparation for the separation into gametes.