Ohio Assessment for Educators (OAE) Integrated Science (024) Practice Exam

What is the expected result of sickle cell anemia on an individual's health?

1. Increased oxygen transport

2. Chronic pain and fatigue

3. Excessive lactation

4. Improved muscle growth

The correct answer is: Chronic pain and fatigue

Sickle cell anemia is a genetic blood disorder that affects hemoglobin, the molecule in red blood cells responsible for carrying oxygen throughout the body. In individuals with this condition, the red blood cells become rigid and shaped like a sickle or crescent moon, rather than the typical disc shape. This abnormal shape leads to several health complications, including chronic pain and fatigue. The sickle-shaped cells can obstruct blood flow in small blood vessels, causing pain crises, which can be severe and debilitating. Additionally, the sickling of red blood cells can result in anemia, as the body struggles to maintain a sufficient number of healthy red blood cells. Anemia contributes to fatigue, as the body is not receiving enough oxygen to function efficiently. Therefore, the expectation of chronic pain and fatigue as a result of sickle cell anemia is well-supported by the clinical manifestations of the disease. In contrast, the other options present outcomes that are not associated with sickle cell anemia. Increased oxygen transport would imply that the red blood cells are functioning properly, which is not the case in this disorder. Excessive lactation is unrelated to sickle cell anemia and is typically linked to hormonal issues or breastfeeding. Improved muscle growth also does not correlate with sickle cell anemia, as